Veterinary Research
ISSN: Online 1994-4659ISSN: Print 1993-5412
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Abstract
The effects of the aqueous leaf extract of Ocimum gratisssimum on testicular histology and spermiogram were investigated using 18 male albino rats. The rats were randomly divided into 3 groups: A-C, each containing 6 rats. Fifty grams of fresh leaves of Ocimum gratisssimum were rinsed, thoroughly blended in 100 mL of distilled water and filtered through filter paper. A 10x10-4 and 5x10-4 mL kg-1 of the filtrate were administered to groups A and B, respectively thrice weekly for 5 weeks. Group C served as control and received distilled water. Histopathology revealed mild to severe congestion and edema as well as germinal tissue erosion of the seminiferous tubules. Spermatozoa motility, concentration, live-dead ratio and semen volume did not show significant changes (p>0.05). However, differences in spermatozoa abnormalities between control and tested groups were highly significant (p<0.01). Mean differences in sperm abnormalities between groups A (28.5), B (13.75) and the control were also greater than calculated Least Significant Difference (LSD) value of 2.146. These findings indicate antifertility properties of Ocimum gratisssimum.
How to cite this article:
Olufisayo O. Leigh and Oluremi E. Fayemi. Effects of Crude Aqueous Extract of Ocimum gratisssimum Leaves on Testicular Histology and Spermiogram in the Male Albino Rat (Wistar strain).
DOI: https://doi.org/10.36478/vr.2008.42.46
URL: https://www.makhillpublications.co/view-article/1993-5412/vr.2008.42.46