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CASE HISTORY
A 73 years old man attended the outpatient clinic with vague abdomen pain. As he had recent episode of right sided hemiplegia, he was taking tablet aspirin 150 mg daily for last 4 weeks. There was no history suggestive of hematemesis or melena. On examination, he was conscious and his vital signs were stable. Gastroscopy was done (Fig. 1).
Question:
What is the diagnosis?
Answer: Double pylorus or Gastroduodenal fistula.
DOUBLE PYLORUS
Double communications between gastric antrum and duodenal bulb is known as double pylorus. It is also known as epipyloric gastoduodenal fistula or antroduodenal fistula. It is an uncommon condition; <100 cases have been reported in literatures since the first case report on 1969 by Smith and Tuttle (1969) and Hegedus et al. (1978). As there is no specific gastrointestinal symptom due to double pylorus, most often it is diagnosed by gastroscopy while performing for other indications.
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Fig. 1: | Gastroduodenal fistula |
Literatures reveal that its overall prevalence varies from 0.06-0.4% with male predominance (male:female ratio 2:1).
It is one of the consequences of peptic ulcer disease, particularly gastric ulcer rather than duodenal ulcer (Smith and Tuttle, 1969; Kothandaraman et al., 1983; Cappelletti et al., 1983).
Proposed mechanism for peptic ulcer induced double pylorus is perforation of underlying muscle layer by ulcer followed by fistula formation and re-epithelialisation (Kothandaraman et al., 1983).
Rohde et al. (1975) described this phenomenon by serial gastroscopy examinations in ulcer disease patients.
Association of helicobacter pylori has been observed as a case report series (Safatle-Ribeiro et al., 1999; Akazawa et al., 2005).
There are no reports regarding long-term complications of double pylorus. Even though, there is no specific medical therapy to asymptomatic double pylorus, those who has had gastric outlet obstruction by double pylorus, separation of mucosal bridge between the two openings by endoscopically using sphincterotome has successfully relieve gastric outlet obstruction symptoms (Graham et al., 1994).
Prem Nair, Venkadeswaran Anantha Narayanan, Joye Varghese and Vallath Balakrishnan. Double Pylorus.
DOI: https://doi.org/10.36478/sjour.2010.7.8
URL: https://www.makhillpublications.co/view-article/1816-3211/sjour.2010.7.8