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Research Journal of Pharmacology

ISSN: Online 1993-6019
ISSN: Print 1815-9362
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A Study on Evaluation of Antidiabetic Activity of A Polyherbal Formulation (Diabestop)

Md. Amir Alam and Md. Gufran Ahmad
Page: 15-19 | Received 31 Jan 2024, Published online: 11 Mar 2024

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Abstract

A polyherbal anti‐diabetic formulation was prepared from leaves of Momordica chirentia, Ocimum sanctum, Azadirachta indica and buds of Piper longum. The blood glucose lowering capacity of the formulation was studied at 100mg/kg dose at white albino rats of wistar strain and compared with standard drug Glibenclamide at 5mg/kg. Anti‐diabetic activity was analyzed in intraperetoneally injected alloxan (150 mg/kg) induced diabetic rats. The various biochemical parameters studied were serum glucose, urea, creatinine, cholesterol, triglycerides, SGOT and SGPT level. The formulation was found to be effective in lowering blood glucose level and in normalizing other organ function significantly.


How to cite this article:

Md. Amir Alam and Md. Gufran Ahmad. A Study on Evaluation of Antidiabetic Activity of A Polyherbal Formulation (Diabestop).
DOI: https://doi.org/10.36478/10.59218/makrjp.2024.1.15.19
URL: https://www.makhillpublications.co/view-article/1815-9362/10.59218/makrjp.2024.1.15.19