Prostate cancer is a leading cause of death among men and is the second most common cancer worldwide. The present study assessed the effects of obesity on the serum levels of free and total prostate‐specific antigen. 84 men patients in age ranged 20‐60 years were enrolled. Patients were classified into four BMI groups according to the WHO BMI classification such as normal BMI (18.5‐24.9), overweight (25‐29.9), obese (30‐34.9) and severe obesity (35‐39.9). Serum tPSA and fPSA was measured by using tPSA and fPSA utilizing ELISA technique. Age group 20‐40 years had 34 and 40‐60 years had 50 patients. Out of 84 patients, 16 were normal, 24 were overweight and 20 were obese and 24 were severe. The mean tPSA (ng/ml) level in normal was 1.75, overweight was 1.70, obese was 1.72 and severe obese was 1.42. The mean fPSA (ng/ml) level in normal was 0.59, in overweight was 0.57, in obese was 0.51 and in severe obese was 0.46. There was no relationship between obesity and prostate specific antigen.
M. Vengatesh and M.K. Suresh. Evaluation of the Impact of Obesity on Blood Levels of Prostate‐Specific Antigen, Both Free and Total in a Tertiary Care Hospital.
DOI: https://doi.org/10.36478/makrjms.2025.3.46.49
URL: https://www.makhillpublications.co/view-article/1815-9346/makrjms.2025.3.46.49