Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Perforative peritonitis poses a significant clinical challenge, necessitating prompt diagnosis and effective management. Central to this is the utilization of peritoneal fluid culture and antibiotic sensitivity testing to guide therapeutic interventions. This study aimed to investigate the clinical, microbiological, and therapeutic aspects of perforative peritonitis. A prospective observational study was conducted at the Department of General Surgery, involving 80 consecutive patients diagnosed with perforative peritonitis. Clinical and demographic data were collected and peritoneal fluid samples were subjected to culture and antibiotic sensitivity testing. Descriptive statistics and comparative analyses were performed to elucidate the findings. Peritoneal fluid analysis revealed elevated white blood cell counts and protein concentrations, indicative of an inflammatory response. Microbiological analysis identified a polymicrobial etiology, with Escherichia coli, Klebsiella pneumoniae and Enterococcus faecalis being the most commonly isolated pathogens. Antibiotic sensitivity testing demonstrated varying degrees of susceptibility with metronidazole, meropenem and ceftriaxone exhibiting high efficacy. This study provides comprehensive insights into the clinical and microbiological characteristics of perforative peritonitis, emphasizing the importance of early diagnosis and tailored antibiotic therapy in improving patient outcomes.
How to cite this article:
K. Anand Goud. Assessment of Peritoneal Fluid Culture and Antibiotic Sensitivity in Patients with Perforative Peritonitis.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.3.275.278
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.3.275.278