Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Comparative Study to Evaluate the Effect of Intravenous Dexmedetomidine and Intravenous Midazolam to Prolong Intrathecal Bupivacaine Anaesthesia
A. Sirmela, S. Arthi, G. Raja Kantham and Shananth Saravanan
Page: 55-60 | Received 17 Sep 2023, Published online: 17 Oct 2023
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Abstract
Subarachnoid block is one of the most frequently used anaesthetic techniques. The addition of adjuvants to local anesthetics might prolong spinal anaesthesia, decrease the dosage of local anaesthetic, delayed‐onset of postoperative pain and reduced analgesic requirements. Present study was aimed to compare effect of intravenous dexmedetomidine versus intravenous midazolam to prolong intrathecal bupivacaine anaesthesia at a tertiary hospital. Present study was single‐center, prospective, comparative study, conducted in Patients between 18 years and 60 years, ASA I and II, undergoing traumatic lower limb surgeries, renal calculi removal, TURP as elective procedures under spinal/intrathecal anaesthesia, willing to participate in present study. Patients were allocated into one of the three groups, 25 patients each, as group M (midazolam group), group D (dexmedetomidine group) and group NS (normal saline group). 75 ASA I and II patients were included in the study. There was no statistically difference with respect to age, height, weight, duration of surgery and ASA status (p>0.05) and the three groups were comparable. The results displayed that there is a significant difference in time to reach highest sensory levels, two segment regression among the three groups. The mean and Standard deviation of visual analogue score and time for analgesia among three groups were compared. There was a significant difference with respect to VAS. It is lesser in Dexmedetomidine group compared to midazolam and normal saline group (p<0.05) Time to first request for postoperative analgesia was later in the Dexmedetomidine group than in the Midazolam and Normal saline groups (p<0.05). The number of patients requiring rescue analgesia was lesser in Group D than in Group M and Group NS. The incidence of hypotension was found higher in group NS than in group M and D, but there was no significant difference. Intravenous dexmedetomidine provided better spinal block quality by prolonging the sensory block when compared to midazolam.
How to cite this article:
A. Sirmela, S. Arthi, G. Raja Kantham and Shananth Saravanan. Comparative Study to Evaluate the Effect of Intravenous Dexmedetomidine and Intravenous Midazolam to Prolong Intrathecal Bupivacaine Anaesthesia.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.12.55.60
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.12.55.60