Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Cervical cancer is the most frequent genital tract cancer among Indian women. Colposcopy has proven to be a much better screening method for premalignant lesions because it yields faster results, directs the site of biopsy and can be completed in one visit.To critically evaluate the role of colposcopy in women with abnormal looking cervix as a screening and diagnostic tool for cervical cancer by comparing it with pap smear and histopathology wherever indicated.Total 132 women with the clinically unhealthy cervix and with abnormal symptoms were included. Detailed clinical examination was done. Pap smear results were interpreted as per Bethesda classification and Colposcopy findings as per the IFCPC criteria. Women with abnormal pap smear and normal pap smear but unhealthy looking cervix, were subjected to colposcopy. In case of abnormal colposcopy, biopsy was taken. Also cases where Pap smear and colposcopy results were incongruent, biopsy was taken. For colposcopy against histopathology the sensitivity was 90% with specificity of 42.86%. The positive and negative predictive values were 69.23‐75%, with accuracy of 70.5%.For PAP smear against histopathology the sensitivity was 90.4% with specificity of 33.3%. The positive and negative predictive values were 65.51‐71.42%, with accuracy of 66.67%. When findings of PAP smear and colposcopy were compared, there was fair agreement between the findings of PAP smear and histopathology findings, with Kappa value of 0.2 and p value of 0.000538 and chi‐square statistics with yates’ correction is 10.6819 and p‐value is 0.001 (significant). Present study concludes sequential screening is needed for diagnosing cervical precancerous lesions. Sensitivity and specificity of pap smear and colposcopy in our study are at par. They complement each other as specificity is not so high.
How to cite this article:
Shreya Sharma, Suchita Dabhadkar, Vaishali Taralekar and Manju Talathi. Cross Sectional Study to Determine Association Between Abnormal Cervix on Colposcopy and
Histopathology.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.12.428.432
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.12.428.432