Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Colorectal cancer ranks second among the most common tumours of the world according to world cancer report 2000. The vital elements of the pathological assessment of colorectal carcinoma specimen include pathological determination of TNM stage, tumour type, histological grade, resected margin and vascular invasion. Histopathology is the gold standard in diagnosis of gastrointestinal lesions. Biopsies (histopathological interpretation) are sought for specific diagnosis, for determining extent of the disease, response to therapy as well as complications. The study was conducted for a period of two years at the Department of Pathology at Tertiary Health Care. Fivety two resected specimens of colon from patients with all relevant clinical details were included in the study. Tissue was processed routinely by fixing specimen 10% formalin followed by paraffin embedding. Tissue sections of 4‐5 micro meter thickness are taken and was studied in details by staining with H and E stain. IHC and specials stains was used whenever necessary. Majority of the specimens received were of ascending colon and sigmoid colon i.e. 12(23.1%) each, followed by 6 specimens of transverse colon i.e. 11.5%. In 5 cases we received ascending and part of transverse colon (9.6%), in 3 cases we received Ascending colon with ileocolic junction and descending colon specimen i.e. 5.8%. Histopathological diagnosis in resected specimen revealed ischaemic colitis in 23 patients i.e. 44.2% followed by well differentiated adenocarcinoma of colon in 8 patients i.e. 15.4%, chronic non‐specific colitis in 6 patients i.e. 11.5%, moderately differentiated adenocarcinoma of colon in 5 patients i.e. 9.6%. Conclusion‐ Commonly observed lesion on histopathology is Ischaemic colitis (44.2%), well differentiated adenocarcinoma of colon (15.4%) and chronic non‐specific colitis (11.5%).
How to cite this article:
Sambodhi C. Killarikar and N. R. Patil. Studying the Clinical Profile of Colonic Lesions along with Evaluation of Pathological and
Histopathological Findings.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.12.330.335
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.12.330.335