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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Understand the Baseline Prevalence Rate of ESBLs and Multidrug Resistance in Enterobacteriaceae from Different Clinical Sample in a Tertiary Care Hospital Located in Rural Part of Kerala

Ami Chandrakant Patel, Purvi Shantilal Khristi, P. A. Remya and Jeswin Chandrasekhar
Page: 192-197 | Received 15 Nov 2023, Published online: 30 Nov 2023

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https://doi.org/10.36478/10.59218/makrjms.2023.12.192.197

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Abstract

To overcome a problem of antimicrobial resistance and start effective Antimicrobial stewardship program we need to understand the resistance pattern of the organism. This study aimed to deliver the indication of different resistant profiles of clinically isolated Enterobacteriaceae from different source of samples from Al‐Azhar Medical college and Super speciality hospital, prevalence of multidrug resistant (MDR), extensively drug‐resistant (XDR) and pan‐drug resistant (PDR) bacteria. A total of 432 Gram‐negative bacteria were collected from different sources (urine, pus, sputum, ET aspirate, vaginal swab, catheter tip, ear swab, throat swab, aspirated body fluid). Out of all Gram negative bacteria Enterobacteriaceae accounted for 353 (81.71%). Samples were sub cultured and identified according to their cultural characteristics and biochemical tests. Antimicrobial susceptibility test was performed for 24 antibiotics from 11 categories against all isolated Enterobacteriaceae according to the recommendation of Clinical and Laboratory Standards Institute (CLSI). The result showed that out of 432 Gram negative isolates, Escherichia coli and Klebsiella species were predominant isolates with the percentage of 40.97‐37.5% respectively. Rate of ESBL was highest among E.coli followed by Enterobacter species 52.54‐50% respectively. The MDR rate was highest among Klebsiella species followed by E.coli 46.29‐42.93% respectively.

How to cite this article:

Ami Chandrakant Patel, Purvi Shantilal Khristi, P. A. Remya and Jeswin Chandrasekhar. Understand the Baseline Prevalence Rate of ESBLs and Multidrug Resistance in Enterobacteriaceae from Different Clinical Sample in a Tertiary Care Hospital Located in Rural Part of Kerala.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.12.192.197
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.12.192.197