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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Correlation of Blood Neutrophil/Lymphocyte Ratio and Pseudoexfoliation Syndrome

Rhutuja Deo and Rekha Khandelwal
Page: 39-43 | Received 22 Jul 2023, Published online: 18 Sep 2023

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Abstract

To study the relationship between blood neutrophil/lymphocyte ratio (NLR) and pseudoexfoliation syndrome. A cross sectional study was carried out at a tertiary care eye hospital attached to academic institute of Central India for a period of 12 months. Forty patients with pseudoexfoliation glaucoma (PXG), 47 patients of pseudoexfoliation syndrome (PXS) and 56 healthy controls were enrolled in this study. Complete ophthalmological examination and complete blood count measurements were performed. Patients with inflammatory, postoperative, traumatic or infective ocular conditions were excluded. Neutrophil/lymphocyte ratio was measured in all patients by Siemens ADVIA 2120 Heamatology system. The mean age in PXS was 69.09±5.88 years, 69.10±6.82 years in PXG and 67.43±5.39 years in control group. Metabolic comorbidities like diabetes and hypertension were similar in both the groups. The mean NLR values in PXS were 2.21±0.89, 2.57±1.47 in PXG and 1.68±0.27 in control group There was a statistically significant difference of NLR between PXS, PXG and control group (p<0.0001) obtained by ANOVA test. NLR was significantly higher in patients with pseudoexfoliation syndrome. This may indicate the heightened inflammatory response in ocular pseudoexfoliation syndrome further leading to pseudoexfoliation glaucoma.


How to cite this article:

Rhutuja Deo and Rekha Khandelwal. Correlation of Blood Neutrophil/Lymphocyte Ratio and Pseudoexfoliation Syndrome.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.10.39.43
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.10.39.43