Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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A Comparative Analysis Between Intrathecal Isobaric Ropivacaine 0.75% Plus Dexmedetomidine and Isobaric Ropivacaine 0.75% Along with Fentanyl for Lower Abdominal and Lower Limb Surgeries
Raja Damarla and B.J. Kavitha Kumari
Page: 201-205 | Received 20 Aug 2013, Published online: 31 Oct 2013
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Abstract
A prospective randomized controlled study was conducted involving 60 patients belonging to ASA group I and II coming for lower abdominal and lower limb surgery. They were randomly divided into 2 groups of 30 each. Group RD received 2ml of 0.5% isobaric Ropivacaine plus Dexmedetomidine 5 μg. Group RF received 2ml of 0.75% isobaric Ropivacaine plus Fentanyl 20 μg. All patients were premeditate and preloading was done with 1000 ml of ringer lactate. Following institution of subarachanoid block sensory characteristics such as onset of sensory block at T 10, maximum level of block, duration of sensory block and motor blockade characteristics such as onset of motor block, duration and quality of motor blockade were studied. Hemodynamic parameters like heart rate, NIBP and SpO2 were monitored every 5min for one hour. Incidence of side effects such as hypotension, bradycardia and nausea, vomiting and pruritus were noted. Demographics were comparable between both groups. Time of onset of sensory block at T10 level was faster with Dexmedetomidine and Ropivacaine. Total duration of sensory block was longer with Dexmedetomidine compared to Fentanyl as adjuvant to Ropivacaine. Onset of motor block is comparable between both groups and it is not clinically and statistically significant. Total duration of motor block was longer with Dexmedetomidine compared to Fentanyl as adjuvant to Ropivacaine. Hemodynamics in both groups were comparable with no clinical and statistical significance. Maximum height of sensory block and degree of motor block were similar in both groups. Among the side effects, occurrence of bradycardia was more with Dexmedetomidine compared to Fentanyl as adjuvant to Ropivacaine. Other side effects were not clinically and statistically significant.
How to cite this article:
Raja Damarla and B.J. Kavitha Kumari. A Comparative Analysis Between Intrathecal Isobaric Ropivacaine 0.75% Plus Dexmedetomidine and Isobaric Ropivacaine 0.75% Along with Fentanyl for Lower Abdominal and Lower Limb Surgeries.
DOI: https://doi.org/10.36478/10.36478/makrjms.2013.201.205
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2013.201.205