Research Journal of Biological Sciences

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Maxillary Bone Necrosis Following the Use of Bisphosphonates in Patients with Cancer: Management and Case Series

Silvia Tortorici , Francesco Burruano , Luigi Caradonna , Maria Lidia Buzzanca and Paolo Difalco
Page: 925-929 | Received 21 Sep 2022, Published online: 21 Sep 2022

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Abstract

Bisphosphonates are bone-turnover modulating drugs used to treat various diseases such as certain cancers, bone metastasis, bone- and calcium-related disorders, Paget`s disease, osteoporosis and osteopenia. Recently, several preliminary reports have reported the insurgence of osteonecrosis of the mandible and/or maxilla, associated with intravenously administered bisphosphonates. This case series describes the effects of bisphosphonates used in the treatment of certain cancers on oral bone tissues.

How to cite this article:

Silvia Tortorici , Francesco Burruano , Luigi Caradonna , Maria Lidia Buzzanca and Paolo Difalco . Maxillary Bone Necrosis Following the Use of Bisphosphonates in Patients with Cancer: Management and Case Series.
DOI: https://doi.org/10.36478/rjbsci.2008.925.929
URL: https://www.makhillpublications.co/view-article/1815-8846/rjbsci.2008.925.929