Mohamed Morad, Ashraf Elkomy, Soad Belih, Mohamed Aboubakr,
Biochemical Changes Following Water Medication of Amoxicillin in Broiler Chickens,
Research Journal of Pharmacology,
Volume 13,Issue 4,
2019,
Pages 42-46,
ISSN 1815-9362,
rjpharm.2019.42.46,
(https://makhillpublications.co/view-article.php?doi=rjpharm.2019.42.46)
Abstract: The effect of amoxicillin on some biochemical
changes in broiler chickens was investigated in 30
apparently healthy broiler chickens. The chickens were
divided into 3 groups and treatment was orally
administered in drinking water for 5 consecutive days.
Group 1; Untreated control, group 2; Treated with
amoxicillin (10 mg kg1 b.wt.) and group 3; Treated with
amoxicillin (20 mg kg1 b.wt.). Blood samples were taken
at the end of experiment, serum samples were used for
biochemical analysis of AST, ALT, total protein, albumin,
creatinine and uric acid. Amoxicillin in both doses
produce an elevation in AST, ALT, creatinine and uric
acid and non-significant elevation in total protein and
albumin. In conclusion, administration of amoxicillin in
both doses (10 and 20 mg kg1 b.wt.) produces some
biochemical changes and these changes was transient.
Care must be taken when used amoxacillin therapeutically
in poultry farms because of their adverse effects on liver
and kidney functions.
Keywords: Amoxicillin;broilers;biochemical;water;protein;albumin