Khaled Z. Alawneh, Liqaa A. Raffee, Haytham A. Al Ewaidat, Ahed J. Alkhatib,
The Impact of Exposure to Medical Radiation on Lead (Pb+2) and
Thyroid Function Test,
Research Journal of Medical Sciences,
Volume 12,Issue 1,
2018,
Pages 31-34,
ISSN 1815-9346,
rjmsci.2018.31.34,
(https://makhillpublications.co/view-article.php?doi=rjmsci.2018.31.34)
Abstract: Exposure to radiation has health impacts that extend to a long time and may deteriorate the biological
functions of various organs. The objectives of the present study were to determine the levels of lead (Pb+2) and
thyroid function test among study participants. A total of 100 subjects were selected of whom 50 subjects were
workers in Radiology Department at King Abdulla University hospitals and 50 control subjects. A blood sample
was with drawn from each participant to assess the levels of lead (Pb+2), T3, T4 and TSH. We analyzed the data
using descriptive statistics to determine frequencies and percentages, means and standard deviations to
present study variables. The differences in means were examined using independent t-test while Pearson
correlation was used to test the correlation of study variables. Significance was considered at p = 0.05. Study
findings showed that the mean lead (Pb+2) in persons who were exposed to medical radiation was
7.89±3.73 μg/dL and this was significantly (p = 0.000) lower than that of control subjects (11.9±2.58 μg/dL). No
significant variations in the difference of means for T3 and TSH were observed in study groups. A significant
difference in means was observed for T4 (p = 0.025). A significantly negative correlation was observed between
the lead level of study subjects and control subjects (p = 0.000). Other significantly positive correlations were
observed between lead (Pb+2) of patients and TSH-patients (p = 0.008), T3 of patients and TSH of patients
(0.033), T4 of patients and TSH of patients (p = 0.000). Taken together, our data demonstrated for the first time
that exposure to radiation decreases the levels of blood lead and impacts thyroid function tests.
Keywords: Radiation;thyroid function test;lead (Pb+2);T3;T4;TSH