Aliasghar  Sadeghi, Sara  Bonabi, Parvin  Showrang, Hamidreza  Khodaei, Behnaz  Mahdavi, Mehrdad  Modaresi, 
    Effects of Commercial Colostrums Replacement (Globigen<sup>&reg;</sup>) on Health and Homo-Immune Parameters in Newborn Calf,
    Research Journal of Biological Sciences,
    Volume 9,Issue 4,
    2014,
    Pages 135-139,
    ISSN 1815-8846,
    rjbsci.2014.135.139,
    (https://makhillpublications.co/view-article.php?doi=rjbsci.2014.135.139)
    Abstract: The neonatal calves, due to their species and special placenta&#146;s structure are born without immune system for contrasting the pathogenic factors and rely on the Ig supply of colostrums through passive immunity transfer. The goal (purpose) of this study was surveying the effects of commercial colostrums (Globigen) on calves health, immunity and blood factors. Total 21 Holstein calves were selected in 3 groups in a random model in this study. The experimental group was as follow: Group 1 (7 calves)-control group fed with maternal colostrums. Total weight = 5.5 kg maternal colostrums in 24 h. Treatment 2 (7 calves) fed with half maternal colostrums+half Globigen<sup>&reg;</sup> Colostrums. Total weight = 5.5 kg in 24 h (2.75 kg maternal colostrums+2.75 g Globigen<sup>&reg;</sup> Colostrums solved in 2.75 L warm water). Treatment 3 (7 calves) fed with Globigen<sup>&reg;</sup> Colostrums. Total weight = 5.5 kg in 24 h (550 g solved in 5.5 L warm water). Blood samples collected from all calves 2 times: After birth and 24 h after that again and blood factors inclusive serums density of IgG , 1 IgG , IgY, cholesterol, triglycerides and glucose, protein, albumin, globulin, ALT, AST and keratin and also 2 weight and fecal score of the calves were surveyed. The SAS98 software was used for statistics analyses and the Duncan test method between comparison of averages (p&lt;0.05) was used to comparison between averages. In this study, immunoglobulins did not increase by Globigen using. The calf&#146;s weight had additive effect than the treatments in control group. The calves in 2nd group were suffering from diarrhea and the number of mortality in 2nd group was more than the other groups. Base on the obtained results, Globigen use as a colostrums alternative is not practical and this product can only be used as a colostrums supplement.
    Keywords: Globigen;colostrums;calf;immunoglobulin;mortality