Mahboobe  Feizianfard, Ali  Raza Ghateh, Seyed  Mohammad Razavi, Masoud  Barati, Mohammad  Ghasem Aminozarbian, 
    A Histopathological Evaluation of Periradicular Tissues after Root Canal Filling with Gutta-Percha/AH<SUB>26</SUB> or Resilon/Epiphany in Dogs&#146; Teeth,
    Research Journal of Biological Sciences,
    Volume 6,Issue 3,
    2011,
    Pages 108-113,
    ISSN 1815-8846,
    rjbsci.2011.108.113,
    (https://makhillpublications.co/view-article.php?doi=rjbsci.2011.108.113)
    Abstract: Root canal obturation is a critical factor in success or failure of a root canal treatment. The material that is used for root canal obturation must be able to provide a perfect seal. The aim of this study was to evaluate <I> in vivo</I> the response of the periradicular tissues after endodontic treatment and root filling with gutta-percha/AH<SUB>26</SUB> or resilon/epiphany in dogs&#146; teeth without coronal seal. About 40 root canals with vital pulps in 2 dogs were instrumented and obturated in a single session and randomly assigned to two groups based on kind of root filling; gutta-percha/AH<SUB>26</SUB> or resilon/epiphany. After 3 and 6 months, the animals were euthanized and the jaws were removed and submitted for histologic processing. Longitudinal sections were obtained and stained with hematoxylin and eosin and examined under light microscopy. Inflammatory status was determined by pathologist and analyzed using Wilcoxon and Mann-Whitney tests. No significant difference found between the two groups in 3 and 6 months (p&gt;0.05). Also, no significant difference was observed in the intensity of inflammation in group gutta-percha/AH<SUB>26</SUB> between 3 and 6 months (p&gt;0.05). But significant difference was observed in the intensity of inflammation in group resilon/epiphany between 3 and 6 months (p&lt;0.05). Under circumstances of this study, there was no apparent advantage of using resilon/epiphany over gutta-percha/AH<SUB>26</SUB> and in controlled conditions both of these materials provide comparable seal. This study also showed the importance of the coronal restoration in preventing unfavorable periradicular tissue reaction.
    Keywords: root canal filling materials;Iran;AH26;resilon;gutta-percha;tissue reaction