Azita Fath  Negad Kazemi, Fahime  Sehhatie, Nilofar  Sattarzade, Mehrangiz  Ebrahimi Mameghani, 
    The Predictive Value of Urinary Calcium to Creatinine Ratio, Roll-Over Test and BMI in Early Diagnosis of Pre-Eclampsia,
    Research Journal of Biological Sciences,
    Volume 5,Issue 2,
    2010,
    Pages 183-186,
    ISSN 1815-8846,
    rjbsci.2010.183.186,
    (https://makhillpublications.co/view-article.php?doi=rjbsci.2010.183.186)
    Abstract: Pre-eclampsia is a common complication of pregnancy and a major cause of maternal and perinatal morbidity and mortality. Therefore, predicting of pre-eclampsia would help achieving better results of midwifery care. Several biophysical and biochemical tests have been investigated for early detection of PE; however, none of them combines have shown accuracy and simplicity necessary to predict PE. The purpose of this study was to use a combination of tests for early prediction of pre-eclampsia. This study was performed at healthy centers of Tabriz in 1386. This was a prospective study that performed on 400 nulliparous women between the 28 and 32 weeks of gestation. At first weight, height, blood pressure on left position and supine position was measured and their sample of urine was catches for calcium and creatinine measuring. These women were followed until delivery. Of total 400 women 23 women developed pre-eclampsia.Using the ROC, urinary calcium-creatinine a <0.068 showed a sensitivity 35% and specificity 93%. BMI >28.88 showed a sensitivity 61% and specificity 92%. Roll-over test >20 mm Hg showed a sensitivity 52% and specificity 95%. When all of them were positive, they showed a sensitivity 17% and specificity 99.5%. The combination of three tests has low sensitivity, however it has high specificity for refusing of pre-eclampsia.
    Keywords: Predictive value;pre-eclampsia;calcium to creatinine ratio;roll-over test;body mass index;Iran