H.I.G. Bastos  , R.B. Freire  , H.R. Borba  , C.D. Coelho  , A.F. Rodrigues  , G.F. Dire  , 
    The Effect of a Natural Solution of Coconut Water on the Macrophage Cultures: A Morphological Analysis,
    Research Journal of Biological Sciences,
    Volume 3,Issue 12,
    2008,
    Pages 1437-1443,
    ISSN 1815-8846,
    rjbsci.2008.1437.1443,
    (https://makhillpublications.co/view-article.php?doi=rjbsci.2008.1437.1443)
    Abstract: Coconut (<I>Cocos nucifera</I> L.) is a monocotyledonous plant of the Arecaceae family. Coconut is a perennial tropical monocotyledon that produces fruit continuously. We aimed to determine the possible effects of coconut water on macrophage cells. Macrophages cells were obtained by Wistar rats and treated with coconut water solution during 30 and 60 min. Morphology microscope analysis has been done. Due to the analysis of the results it was observed that in the quantitative and in the qualitative analysis was observed the apoptotic effect of the coconut water in the cells culture treated during 30 and 60 min. It may be suggested that apoptotic effect of the referred studied solution would be related to the possible presence of a substance which may alter the imbalanced expression of iNOS/eNOS in the macrophage cells.
    Keywords: Macrophage;coconut water;nitric oxide;apoptosis;morphology