TY  - JOUR
T1  - Biochemical Changes Following Water Medication of Amoxicillin in Broiler Chickens
AU - Morad, Mohamed AU - Elkomy, Ashraf AU - Belih, Soad AU - Aboubakr, Mohamed 
JO  - Research Journal of Pharmacology
VL  - 13
IS  - 4
SP  - 42
EP  - 46
PY  - 2019
DA  - 2001/08/19
SN  - 1815-9362
DO  - rjpharm.2019.42.46
UR  - https://makhillpublications.co/view-article.php?doi=rjpharm.2019.42.46
KW  - Amoxicillin
KW  -broilers
KW  -biochemical
KW  -water
KW  -protein
KW  -albumin
AB  - The effect of amoxicillin on some biochemical
changes in broiler chickens was investigated in 30
apparently healthy broiler chickens. The chickens were
divided into 3 groups and treatment was orally
administered in drinking water for 5 consecutive days.
Group 1; Untreated control, group 2; Treated with
amoxicillin (10 mg kg<sup>&#150;1</sup> b.wt.) and group 3; Treated with
amoxicillin (20 mg kg<sup>&#150;1</sup> b.wt.). Blood samples were taken
at the end of experiment, serum samples were used for
biochemical analysis of AST, ALT, total protein, albumin,
creatinine and uric acid. Amoxicillin in both doses
produce an elevation in AST, ALT, creatinine and uric
acid and non-significant elevation in total protein and
albumin. In conclusion, administration of amoxicillin in
both doses (10 and 20 mg kg<sup>&#150;1</sup> b.wt.) produces some
biochemical changes and these changes was transient.
Care must be taken when used amoxacillin therapeutically
in poultry farms because of their adverse effects on liver
and kidney functions.
ER  -