TY  - JOUR
T1  - Causes of Hospital Admission among Patients Receiving Highly Active Antiretroviral Therapy
AU - Thinyane, Keneuoe H. AU - Cooper, Varsay L.J. 
JO  - Research Journal of Medical Sciences
VL  - 7
IS  - 5-6
SP  - 130
EP  - 133
PY  - 2013
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2013.130.133
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2013.130.133
KW  - hospital admission
KW  -HIV
KW  -opportunistic infections
KW  -HIV
KW  -patient
AB  - Highly active antiretroviral therapy has substantially improved 
  the prognosis for HIV-infected patients globally. However, HIV infection remains 
  a major cause of morbidity and mortality in many developing countries. The main 
  objective of this study was to investigate the causes of hospital admission 
  in patients receiving antiretroviral therapy in Lesotho. A 4 months cross-sectional 
  study of HIV-infected, ART-treated adults admitted to the male and female medical 
  wards at Queen Elizabeth II Referral Hospital in Maseru, Lesotho. A 96 patients 
  enrolled, 62.5% were male and the median CD4 count on admission was 101 cells/μL 
  (IQR 22-224). A 69.8% of the study participants had been receiving HAART for 
  <6 months and 97.9% of all patients were on a first line NNRTI-based regimen. 
  Patients were admitted for the management of opportunistic infections (71.9%), 
  non-infectious HIV-related diseases (24.0%) and adverse drugs reactions (18.8%). 
  The most frequent principal diagnoses were tuberculosis (45.8%), AZT-induced 
  anaemia (11.5%), pneumonia (9.4%) and immune-inflammatory reconstitution syndrome 
  (7.3%). In-hospital mortality among the study participants was 36.5%. HIV-related 
  opportunistic infections are an important cause of hospital admission and mortality 
  in the era of HAART. Efforts are needed to encourage patients to present early 
  to HIV care. In addition, patient monitoring should be improved in order to 
  facilitate early detection and management of treatment failure.
ER  -