TY  - JOUR
T1  - The Effect of Betamethasone Injection on Sexual Hormones Concentration in Female Mice
AU - Modaresi, Mehrdad AU - Tajaddini, Amir AU - Pirestani, Akbar 
JO  - Research Journal of Biological Sciences
VL  - 9
IS  - 3
SP  - 102
EP  - 104
PY  - 2014
DA  - 2001/08/19
SN  - 1815-8846
DO  - rjbsci.2014.102.104
UR  - https://makhillpublications.co/view-article.php?doi=rjbsci.2014.102.104
KW  - Betamethasone
KW  -LH
KW  -FSH
KW  -strogen
KW  -progestron
KW  -mice
AB  - Betamethasone stimulates production of necessary enzymes for 
  reducing inflammatory responses. This drug is a long-acting steroid which produces 
  quick anti inflammatory effects with long time effect. Effects of betamethasone 
  on sexual hormes of female mice were studied in this study. Mice were divided 
  in 5 groups (control, Placebo and 3 treatments groups) with 10 members in each 
  group. Samples were kept in similar condition be synchronized in estrus cycle. 
  Betamethasone was prepared in 0.1, 0.5 and 1 mg kg<SUP>-1</SUP> doses and injected 
  in peritoneum for 20 days. Control group was not injected while Placebo received 
  normal saline. After 10 injections blood samples were prepared and the amounts 
  of LH, FSH, strogen and progestron hormones were evaluated by RIA method. Obtained 
  results showed that strogen, progesterone and LH were reduced by all treatment 
  significantly whereas FSH was increased in 0.5 and 1 mg kg<SUP>-1</SUP> groups. 
  According to results, betamethasone affects sexual hormones dose dependently 
  and then can affect female sexual potential.
ER  -