TY - JOUR T1 - Efficacy of Omega-3 Fatty Acid Supplementation in Post-Menopausal Hot Flashes: A Randomized Clinical Trial AU - Haghighi, Ladan AU - Ghasemi, Afsaneh JO - Research Journal of Biological Sciences VL - 8 IS - 2 SP - 46 EP - 49 PY - 2013 DA - 2001/08/19 SN - 1815-8846 DO - rjbsci.2013.46.49 UR - https://makhillpublications.co/view-article.php?doi=rjbsci.2013.46.49 KW - hot flash KW -Omega-3 KW -post-menopause KW -intensity KW -Tehran AB - Hot flash is an unpleasant sense of hot feeling. The aim of this study was to assess the efficacy of omega-3 supplements in post-menopausal hot flashes. In this randomized trial, 60 post-menopausal patients with moderate to severe hot flashes randomly assigned to receive either 1000 mg omega-3 or placebo every day for 12 weeks. Main outcome measures were daily frequency and intensity of hot flashes at 12 weeks, 6 and 9 months after the intervention. At baseline, there was no statistically significant difference between the two groups in terms of age and duration, intensity and daily frequency of hot flashes. About 8 and 12 weeks after the intervention, omega-3 supplementation was associated with more reduction in the intensity of hot flashes compared to placebo (p = 0.01 and 0.004, respectively). However, it could not decrease significantly the number of daily hot flashes. ER -