TY - JOUR T1 - Biological Evaluation of Some Azole Derivatives in Cooling Fluids (Lubricant Oils) AU - Hassan, Firas Abdullah AU - Younus, Khalid Waleed JO - Research Journal of Biological Sciences VL - 7 IS - 1 SP - 48 EP - 51 PY - 2012 DA - 2001/08/19 SN - 1815-8846 DO - rjbsci.2012.48.51 UR - https://makhillpublications.co/view-article.php?doi=rjbsci.2012.48.51 KW - Azoles KW -cooling fluids KW -pH KW -turbidity KW -culture media KW -microorganism AB - In the present study, a series of five members heterocyclic where used as antimicrobial against the pseudomonas bacteria which have been found in the cooling fluids of industrial purposes. The results showed that the compounds 3 and 5 are relatively higher percentage in killing bacteria than other compounds used in this research indicating that from measuring pH, turbidity and culture media to inhibit the pseudomonas bacteria. After measuring the microorganisms growth of cooling fluids in 3 different periods (1 day, 1 and 2 weeks) by using pH and turbidity measurements enhanced with media culture method, the 2 weeks sample had been taken which showed highest growth of microorganisms meanwhile these azoles derivatives have been used as antimicrobial against the microorganisms which have been found in the cooling fluid of industrial purposes by measuring pH and turbidity enhanced with media culture the results showed that the compound 5 had the best biological activity then compounds 1 and 3 are relatively higher active in killing bacteria from the compounds 2 and 4. That azoles derivative is biologically active as antimicrobial agents in cooling fluids as derivatives of azoles have used as follows: [5- (2,4-dinitrobenzamide)-2-hydrazine]-thiadiazole, 2-mercapto-1, 3, 4-triazole-2, 4-dinitrobenzamide), Dithiophen oxadiazole, Thiophene/furan oxadiazole and Phenyl/pyridine oxadiazole. ER -