TY - JOUR
T1 - Antioxidant Activity and Chemical Constituents of Pupalia lappacea (L.) Juss
AU - , A. Aladedunye Felix AU - , A. Okorie Domingo
JO - Research Journal of Biological Sciences
VL - 3
IS - 7
SP - 783
EP - 785
PY - 2008
DA - 2001/08/19
SN - 1815-8846
DO - rjbsci.2008.783.785
UR - https://makhillpublications.co/view-article.php?doi=rjbsci.2008.783.785
KW - Pupalia lappacea (L.) Juss. (Amaranthaceae)
KW -ecdysteroid
KW -20-hydroxyecdysone
KW -antioxidant activity
KW -saropeptate
AB - Phytochemical analysis of foliage of Pupalia lappacea (L.) Juss (Amaranthaceae) afforded 8 compounds, namely; 1-docosanol, stearic acid, stigmasterol, -sitosterol, N-benzoyl-L-phenylalaninol acetate, -sitosterol-3-O- -D-glucopyranoside, stigmasterol-3-O- -D-glucopyranoside and 20-hydroxyecdysone. The ecdysteroid, 20-hydroxyecdysone, constitutes nearly 0.3% of the dry weight and 13% of the dichloromethane extracts of the plant, making Pupalia lappacea a probable commercial source for this important ecdysteroid. Both the hexane and dichloromethane extracts showed significant antioxidant activity with the dichloromethane exhibiting an IC50 comparable to that of BHT, a synthetic antioxidant. All the isolated compounds are reported for the first time in the genus.
ER -