TY  - JOUR
T1  - A Clinical Case of Aortic Root Abscess Caused by Brucellosis: Molecular Diagnosis, Surgical Treatment and Successful Management
AU - E. Ahmed, Mohamed AU - A. Ali, Ibtisam AU - M. El Sanousi, Enaam AU - E. Aradaib, Imadeldin 
JO  - The Cardiology
VL  - 5
IS  - 1
SP  - 1
EP  - 3
PY  - 2010
DA  - 2001/08/19
SN  - 1811-8194
DO  - tcard.2010.1.3
UR  - https://makhillpublications.co/view-article.php?doi=tcard.2010.1.3
KW  - PCR
KW  -bacterial nucllein
KW  -infectious bacteria
KW  -B. Melitensis
KW  -B. Abortus
KW  -Sudan
AB  - Endocarditis is a rare complication of brucellosis, often fatal and the treatment is controversial. In the present report, an unusual case of repeated bacteraemia caused by <I>Brucella melitensis</I> in a 17 years old Sudanese patient is described. The patient was strongly positive for brucellosis by serological reaction but conventional microbiological cultures form blood and valve tissue were largely unsuccessful. However, PCR detected nucleic acid sequence specific for <I>Brucella melitensis</I>. The patient was successfully treated by a combination of surgical resection and antibiotics. It is suggested that simultaneous application of bacterial culture and PCR could be more useful than either test alone for the diagnosis of brucellosis in suspected patients.
ER  -