@article{MAKHILLRJBS20138211393, title = {Efficacy of Omega-3 Fatty Acid Supplementation in Post-Menopausal Hot Flashes: A Randomized Clinical Trial}, journal = {Research Journal of Biological Sciences}, volume = {8}, number = {2}, pages = {46-49}, year = {2013}, issn = {1815-8846}, doi = {rjbsci.2013.46.49}, url = {https://makhillpublications.co/view-article.php?issn=1815-8846&doi=rjbsci.2013.46.49}, author = {Ladan and}, keywords = {hot flash,Omega-3,post-menopause,intensity,Tehran}, abstract = {Hot flash is an unpleasant sense of hot feeling. The aim of this study was to assess the efficacy of omega-3 supplements in post-menopausal hot flashes. In this randomized trial, 60 post-menopausal patients with moderate to severe hot flashes randomly assigned to receive either 1000 mg omega-3 or placebo every day for 12 weeks. Main outcome measures were daily frequency and intensity of hot flashes at 12 weeks, 6 and 9 months after the intervention. At baseline, there was no statistically significant difference between the two groups in terms of age and duration, intensity and daily frequency of hot flashes. About 8 and 12 weeks after the intervention, omega-3 supplementation was associated with more reduction in the intensity of hot flashes compared to placebo (p = 0.01 and 0.004, respectively). However, it could not decrease significantly the number of daily hot flashes.} }